Coronary disease & ACSCohort study

1-Year Outcomes of Drug-Coated Balloon Angioplasty Versus Drug-Eluting Stent for Coronary Artery Bypass Graft Lesions

JACC Cardiovasc IntervPublished

  • Registry-based cohort study
  • nationwide registry
  • multivariable adjusted

Authors' conclusion

Stentless PCI with DCB was frequently used in patients undergoing PCI for bypass graft lesions in Japan and was not associated with a significant difference in 1-year clinical outcomes compared with contemporary DES-based PCI strategies.

Study context

Population
Patients undergoing percutaneous coronary intervention (PCI) for bypass graft lesions, J-PCI OUTCOME registry, Japan, 2017–2020
Participants
610 PCIs
Exposure
Drug-coated balloon (DCB)-only vs drug-eluting stent (DES) PCI for bypass graft lesions
  • DCB-onlyn = 184
Outcome
MACE:
  • All-cause death
  • ACS
  • Stroke
Follow-up
Within 1 year after PCI

Main finding

1-year MACE · 1 year

Adjusted hazard ratio

1.01

95% CI 0.58–1.76

P = 0.96

By group

DCB-only vs DES
adjusted HR 1.01 (95% CI 0.58–1.76); P = 0.96

As reported in the abstract

Observational data: associations, not effects.

Secondary outcomes

Individual MACE components, major bleeding, planned repeat revascularization

No statistically significant differences

Original publication

1-Year Outcomes of Drug-Coated Balloon Angioplasty Versus Drug-Eluting Stent for Coronary Artery Bypass Graft Lesions. JACC Cardiovasc Interv. Published 31 August 2026. doi:10.1016/j.jcin.2026.06.023

Summarised from the published abstract; every number is checked against it