Cardiometabolic & kidneyCohort study
10-Year Cardiovascular Risk in Patients With Newly Diagnosed Type 2 Diabetes Mellitus
- Matched cohort study
- sex- and age-matched
- nationwide
Authors' conclusion
Newly diagnosed T2DM increased 10-year CVD risk across both sexes and all age groups, especially among younger patients, with CVD occurring ≤12 years earlier than in general population individuals.
Study context
- Population
- Danish patients with newly diagnosed T2DM and matched general population, without prior atherosclerotic cardiovascular disease (CVD)52,471 CVD events
- Participants
- 142,587 vs 388,410
- Exposure
- Newly diagnosed T2DM vs general population
- T2DMn = 142,587
- General populationn = 388,410reference
- Outcome
- CVD (MI, stroke and fatal CVD)
- Follow-up
- 10 years
Main finding
As reported in the abstract
10-year CVD risk, age 40–49 years
Each group vs general populationSubdistribution hazard ratio (95% CI)
T2DM
1.91(1.76–2.07)
- T2DM
- risk difference 2.8%
Observational data: associations, not effects.
Further findings
Age at which 10-year CVD risk of 5% reached
Age
- Men with T2DM
- 43
- Men without T2DM
- 55
- Women with T2DM
- 51
- Women without T2DM
- 61
Original publication
10-Year Cardiovascular Risk in Patients With Newly Diagnosed Type 2 Diabetes Mellitus. J Am Coll Cardiol. Published 17 October 2023. doi:10.1016/j.jacc.2023.08.015
Summarised from the published abstract; every number is checked against it