Cardio-oncology & otherGuideline or statement

18F-FDG PET/CT and Radiolabeled Leukocyte SPECT/CT Imaging for the Evaluation of Cardiovascular Infection in the Multimodality Context

JACC Cardiovasc ImagingPublished

  • Multisocietal expert consensus document (modified Delphi)

Recommendations

As issued by the authors

  1. 18F-FDG PET/CT and SPECT/CT leukocyte scintigraphy can enhance evaluation of suspected cardiovascular infection by increasing diagnostic accuracy, identifying extracardiac involvement, and assessing cardiac implanted device pockets, leads and all portions of ventricular assist devices

  2. Consensus diagnostic features: focal/multifocal or diffuse heterogenous intense 18F-FDG uptake on valvular and prosthetic material, perivalvular areas, device pockets and leads, and ventricular assist device hardware, persisting on non-attenuation corrected images

  3. Numerous clinical indications, with a larger role in prosthetic valves and cardiac devices, particularly with possible infective endocarditis or after prior equivocal or non-diagnostic imaging

Original publication

18F-FDG PET/CT and Radiolabeled Leukocyte SPECT/CT Imaging for the Evaluation of Cardiovascular Infection in the Multimodality Context. JACC Cardiovasc Imaging. Published 11 March 2024. doi:10.1016/j.jcmg.2024.01.004

Summarised from the published abstract; every number is checked against it