Heart failure & cardiomyopathiesDiagnostic or prognostic study

2-Dimensional Echocardiographic Global Longitudinal Strain With Artificial Intelligence Using Open Data From a UK-Wide Collaborative

JACC Cardiovasc ImagingPublished

  • Diagnostic accuracy study
  • external validation
  • multiexpert consensus reference

Authors' conclusion

Our open-source approach to calculating GLS agrees with experts' consensus as strongly as the individual expert measurements and proprietary machine solutions.

Study context

Population
Apical 4-, 2- and 3-chamber echocardiographic images; external validation on 100 echocardiograms (Unity UK Echocardiography AI Collaborative)
Participants
100 echocardiograms
Comparison
Open machine-learning global longitudinal strain (GLS) (Unity-GLS) vs individual experts and 2 proprietary packages
Outcome
Agreement of GLS with multiexpert consensus measurement

Performance

As reported in the abstract

Agreement with expert consensus GLS
Test or modelMedian absolute errorCorrelation with consensusError
Individual experts2.00 GLS units0.85
Unity-GLS0.911.3
Proprietary A0.732.5
Proprietary B0.792.2

Further findings

OutcomeIndividual expertsUnity-GLSProprietary AProprietary B
Median GLS across 11 expertsmedian −16.1 (IQR −19.3–-12.5)Not reported in the abstractNot reported in the abstractNot reported in the abstract
Rank correlation with multiexpert visual rankingmedian rank correlation 0.720.770.700.74

Original publication

2-Dimensional Echocardiographic Global Longitudinal Strain With Artificial Intelligence Using Open Data From a UK-Wide Collaborative. JACC Cardiovasc Imaging. Published 10 July 2024. doi:10.1016/j.jcmg.2024.04.017

Summarised from the published abstract; every number is checked against it