Guideline or statement

2024 Revision of the level of evidence grading system for European Society of Cardiology (ESC) clinical practice guideline recommendations II: diagnostic tests and prediction models

Eur Heart JPublished

  • Guideline methodology report

Recommendations

As issued by the authors

  1. LOE A

    Diagnostic tests: conclusive evidence of adequate diagnostic ability from at least two high-quality studies

  2. LOE B

    Diagnostic tests: suggestive evidence from one high-quality or at least two moderate-quality studies

  3. LOE C

    Diagnostic tests: preliminary evidence not classified as A or B, incl. evidence from less than two moderate-quality studies, or from expert consensus

  4. LOE A

    Prediction models: conclusive evidence of adequate predictive ability from at least one high-quality derivation and two or more external validation studies of at least moderate quality

  5. LOE B

    Prediction models: suggestive evidence in one or more derivation studies and one or more external validation studies of at least moderate quality

  6. LOE C

    Prediction models: preliminary evidence not classified as A or B, incl. a derivation study of at least moderate quality but with low quality or no external validation, or a derivation study of low quality

Original publication

2024 Revision of the level of evidence grading system for ESC clinical practice guideline recommendations II: diagnostic tests and prediction models. Eur Heart J. Published 21 March 2025. doi:10.1093/eurheartj/ehaf016

Summarised from the published abstract; every number is checked against it