Cardio-oncology & otherGuideline or statement

2025 AHA/ACC Statement on Cost/Value Methodology in Clinical Practice Guidelines (Update From 2014 Statement)

J Am Coll CardiolPublished

  • Scientific statement

Recommendations

As issued by the authors

  1. US cost-effectiveness threshold defined as $120,000 per quality-adjusted life year gained

  2. New level of certainty framework summarizing the strength of the available evidence

  3. Guidance for identifying and synthesizing relevant high-quality evidence, developing economic value statements, and communicating level of certainty in such statements

  4. Special considerations for CV drugs and devices; health equity considerations when interpreting cost-effectiveness analyses (CEAs); reference case defined for future CEAs

Original publication

2025 AHA/ACC Statement on Cost/Value Methodology in Clinical Practice Guidelines (Update From 2014 Statement). J Am Coll Cardiol. Published 25 September 2025. doi:10.1016/j.jacc.2025.05.009

Summarised from the published abstract; every number is checked against it