Coronary disease & ACSRandomised controlled trial
5-Year Outcomes After Bioresorbable Coronary Scaffolds Implanted With Improved Technique
- Randomised controlled trial
- blinded
- multicentre (147 sites)
Patients, clinical assessors and event adjudicators blinded; 5-year follow-up completed
Authors' conclusion
In this large-scale, blinded randomized trial, despite the improved implantation technique, the absolute 5-year rate of target lesion failure was 3% greater after BVS compared with CoCr-EES.
Study context
- Population
- Patients with stable or acute coronary syndromes
- Participants
- 2,604 patients
- Comparison
- Bioresorbable vascular scaffolds (BVS) with improved technique vs CoCr-EES
- Primary endpoint
- Target lesion failure
- Follow-up
- 5 years
Primary result
As reported in the abstract
P = 0.03
Further findings
Recurrent angina (centrally adjudicated) · within 5 years · cumulative rate
P = 0.63
Event rates over time
- Slightly greater with BVS than CoCr-EES through 3 years; similar between 3 and 5 years
Safety
Device thrombosis · within 5 years
P = 0.15
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
5-Year Outcomes After Bioresorbable Coronary Scaffolds Implanted With Improved Technique. J Am Coll Cardiol. Published 17 May 2023. doi:10.1016/j.jacc.2023.05.003
Summarised from the published abstract; every number is checked against it