A 0/2-Hour Algorithm Using a Novel Point-of-Care High-Sensitivity Cardiac Troponin I Assay for Suspected Myocardial Infarction

Koechlin, L; Lopez-Ayala, P; Boeddinghaus, J; Sigg, N; Durak, K; Nestelberger, T; Wildi, K; Strebel, I; Bima, P; Crisanti, L; Recuenco, LH; Yueksel, A; Miró, Ò; Martin-Sanchez, FJ; Kawecki, D; Keller, DI; Christ, M; Buser, A; Biefer, HRC; Dzemali, O; Broughton, MN; Mahfoud, F; Mueller, C; APACE investigators

doi:10.1016/j.ahj.2026.107625

Coronary disease & ACS

A 0/2-Hour Algorithm Using a Novel Point-of-Care High-Sensitivity Cardiac Troponin I Assay for Suspected Myocardial Infarction

Am Heart JPublished 13 Oct 2026derivation and internal validation of an assay-specific hs-cTnI-SPINCHIP 0/2h-algorithm

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Authors' conclusion

These findings support the clinical potential of the novel point-of-care hs-cTnI-SPINCHIP assay for accelerated ED decision-making.

Study context

Population: patients with suspected myocardial infarction (MI) in the emergency department (ED)

Outcome: Rule-out safety, rule-in accuracy and triage
Follow-up: Within 2 hours

Performance

As reported in the abstract

Definitive triage within 2 hours

≈80% of patients

Original publication

A 0/2-Hour Algorithm Using a Novel Point-of-Care High-Sensitivity Cardiac Troponin I Assay for Suspected Myocardial Infarction. Am Heart J. Published 13 October 2026. doi:10.1016/j.ahj.2026.107625

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Summarised from the published abstract; every number is checked against it