HypertensionRandomised controlled trial
A Community-Based Intervention for Managing Hypertension in Rural South Asia
- Cluster randomised controlled trial
- rural districts in Bangladesh, Pakistan and Sri Lanka
- 24-month follow-up completed for >90% of participants
Authors' conclusion
In rural communities in Bangladesh, Pakistan, and Sri Lanka, a multicomponent intervention that was centered on proactive home visits by trained government community health workers who were linked with existing public health care infrastructure led to a greater reduction in blood pressure than usual care among adults with hypertension.
Study context
- Population
- Adults with hypertension in rural communities in Bangladesh, Pakistan and Sri Lanka
- Participants
- 2,645 adults · 30 communities
- Comparison
- Multicomponent community intervention vs usual care
- Primary endpoint
- Reduction in SBP
- Follow-up
- 24 months
Primary result
As reported in the abstract
Difference in mean reduction
5.2 mm Hg
95% CI 3.2–7.1
P < 0.001
By group
Intervention vs Usual care
difference in mean reduction 5.2 mm Hg (95% CI 3.2–7.1); P < 0.001
Further findings
| Outcome | difference in mean reduction (mm Hg) (95% CI) | |
|---|---|---|
| Reduction in DBP · 24 months · greater reduction with intervention | 2.8 (1.7–3.9) | |
| −2024Difference, mm Hg (linear scale) |
| Outcome | Intervention | Usual care | RR (95% CI) | |
|---|---|---|---|---|
| BP control (<140/90 mm Hg) | 53.2% | 43.7% | 1.22 (1.10–1.35) | |
| 0.512Relative risk (log scale) |
All-cause mortality
Original publication
A Community-Based Intervention for Managing Hypertension in Rural South Asia. N Engl J Med. Published 20 February 2020. doi:10.1056/nejmoa1911965
Summarised from the published abstract; every number is checked against it