Coronary disease & ACSResearch article
A comprehensive set of per-protocol analyses of the myocardial ischemia and transfusion (MINT) trial
- per-protocol analyses of the Myocardial Ischemia and Transfusion (MINT) trial
- different definitions of adherence (site-reported, time-based, transfusion delay)
- instrumental variable analysis
Study context
- Population
- patients from the Myocardial Ischemia and Transfusion (MINT) trial
- Comparison
- restrictive versus liberal transfusion strategies
Main finding
As reported in the abstract
30-day death or recurrent MI · 30-day
- Analyses based on adherence definitions: restrictive strategy associated with a substantially greater risk of 30-day death or recurrent myocardial infarction (MI)
- Instrumental variable analysis: moderate treatment effect similar to the original ITT result
Original publication
A comprehensive set of per-protocol analyses of the myocardial ischemia and transfusion (MINT) trial. Am Heart J. Published 18 February 2026. doi:10.1016/j.ahj.2026.107382
Summarised from the published abstract; every number is checked against it