HypertensionRandomised controlled trial
A Coordinated Community- and Family-Based Intervention to Control Blood Pressure in Rural China
- Cluster-randomised controlled trial
- 1:1 randomisation
Authors' conclusion
In rural China, a coordinated community- and family-based intervention significantly shifted the population distribution of SBP toward lower levels over 6 months.
Study context
- Population
- Adults aged 40 to 80 years in rural Chinese village clusters, irrespective of blood pressure (BP) level or hypertension status80 village clusters
- Participants
- 8,001 adults
- Comparison
- Coordinated community- and family-based intervention vs usual care
- Primary endpoint
- Between-group difference in change in SBP from baseline
- Follow-up
- 6 months
Primary result
Change in SBP
Adjusted between-group difference
−10.7 mm Hg
95% CI −11.8 to −9.6
By group
Intervention
6.0
mean fall · mm Hg
Usual care
5.1
mean increase · mm Hg
Intervention vs Usual care
adjusted between-group difference −10.7 mm Hg (95% CI −11.8 to −9.6)
As reported in the abstract
Further findings
| Outcome | Intervention | Usual care | adjusted OR (95% CI) | |
|---|---|---|---|---|
| BP <130/80 mm Hg · 6 months | 46.2% | 23.6% | 5.3 (4.3–6.6) | |
| 0.10.31310Adjusted odds ratio (log scale) |
Change in systolic blood pressure (SBP) · 12 months
- Adjusted between-group difference in SBP at 12 months
- −3.7 mm Hg (95% CI: −4.9 to −2.6 mm Hg)
Safety
Serious adverse events
Original publication
A Coordinated Community- and Family-Based Intervention to Control Blood Pressure in Rural China. J Am Coll Cardiol. Published 26 August 2026. doi:10.1016/j.jacc.2026.07.045
Summarised from the published abstract; every number is checked against it