Heart failure & cardiomyopathies
A nationwide study of the economic burden of obstructive hypertrophic cardiomyopathy in France
Authors' conclusion
Obstructive HCM has a high economic burden driven by cardiovascular hospitalizations. Higher disease severity yielded higher costs associated with medical care and sick leave than lower classes. Results support need for new therapies to improve both symptoms and disease severity.
Study context
- Population
- Adults (≥18) with obstructive hypertrophic cardiomyopathy (HCM) and at least one disease related hospitalization during 2012–18, in France; patients with <1-year follow-up or phenocopy disorders excludedpatients identified, 30,228 patient-year (PYs)
- Participants
- 6,823 adults
- Exposure
- Costs by disease severity class (New York Heart Association (NYHA) class); annual cost before and after septal reduction therapies (SRT)
- Outcome
- Total burden
- Follow-up
- Mean (standard deviation) 4.4 (2.5) years
Methodological detailsdata from the French National Health Data System
- Data from the French National Health Data System
Main finding
As reported in the abstract
Total burden
€388 million
Cost per PY
€12 824
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Cost per patient year by NYHA class | I €8881 · IV €22 818 |
| Mean sick-leave-related costs per PY | I mean €310 · II mean €673 · III mean €757 · IV mean €774 |
- Cost per patient year by NYHA class: higher NYHA class was associated with higher cost per patient year
Hospitalizations share of costs
- Hospitalizations accounted for most costs
- 54%
- Cardiovascular-related hospitalizations
- 71%
- Disease-related
- 46%
Mean cost per PY 1 year before vs. after SRT, including the intervention
- Before SRT
- €13 726
- After SRT
- €18 565
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
A nationwide study of the economic burden of obstructive hypertrophic cardiomyopathy in France. Eur Heart J Qual Care Clin Outcomes. Published 4 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →