Arrhythmias & electrophysiology
A new left atrial appendage isolation strategy for persistent atrial fibrillation requiring repeat ablation
Authors' conclusion
LAAI using a linear approach of AML and PML with VOM is feasible and reproducible and results in a low rate of arrhythmia recurrences, most of which are self-limited.
Study context
- Population
- Patients undergoing repeat ablation for persistent atrial fibrillation (AF) in whom LAA isolation (LAAI) was performed via AML and PML ± VOM, 2023–2024
- Participants
- 23 patients
- Outcome
- Durable LAAI and arrhythmia recurrence
- Follow-up
- 1 year
Methodological detailsSystematic remapping at left atrial appendage (LAA) occlusion to assess LAAI durability
- Systematic remapping at LAA occlusion to assess LAAI durability
Main finding
As reported in the abstract
1 year
- Acute LAAI achieved
- all
- VOM successfully performed
- 74%
- Durable LAAI
- 61%
- Arrhythmia recurrence at 1 year (AT more frequent than AF)
- 61%
Observational data: associations, not effects.
Safety
- No evidence of acute thrombus
- No strokes or TIAs occurred
Original publication
A new left atrial appendage isolation strategy for persistent atrial fibrillation requiring repeat ablation. Heart Rhythm. Published 19 December 2025. doi:10.
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