Diagnostic or prognostic study
A Novel Heart Failure Diagnostic Risk Score Using a Minimally Invasive Subcutaneous Insertable Cardiac Monitor
- Diagnostic accuracy study
- 2 observational cohorts
- development and validation data sets
Authors' conclusion
ICM-HFRS provides a multiparameter, integrated diagnostic method with the ability to identify when HF patients are at increased risk of heart failure events.
Study context
- Population
- Patients with NYHA class II/III heart failure (HF) across the EF spectrum, implanted with a subcutaneous insertable cardiac monitor (ICM)
- Participants
- 42 vs 94
- Comparison
- Development vs Validation
- Developmentn = 42
- Validationn = 94
- Outcome
- ICM-based HF risk score (heart failure risk score (HFRS)) performance to predict HF events (sensitivity, unexplained detection rate)
- Follow-up
- Within 30 days
Performance
As reported in the abstract
HFRS performance at high-risk threshold 7.5%
| Test or model | Value | Sensitivity | Unexplained detection rate | Median early warning before heart failure event (HFE) |
|---|---|---|---|---|
| Development | 19 events | 73.7% | 1.4 per patient-year | 47 days |
| Validation | 19 events | 68.4% | 1.5 per patient-year | 64 days |
Original publication
A Novel Heart Failure Diagnostic Risk Score Using a Minimally Invasive Subcutaneous Insertable Cardiac Monitor. JACC Heart Fail. Published 8 November 2023. doi:10.1016/j.jchf.2023.09.014
Summarised from the published abstract; every number is checked against it