Diagnostic or prognostic study

A novel score to predict left ventricular recovery in peripartum cardiomyopathy derived from the ESC EORP Peripartum Cardiomyopathy Registry

Eur Heart JPublished

  • Prognostic model development and internal validation study (registry)
  • multinational registry
  • bootstrap internal validation

Authors' conclusion

A model which accurately predicts LV recovery at 6 months in women with PPCM was derived.

Study context

Population
Women with peripartum cardiomyopathy (peripartum state, HF signs or symptoms, LV ejection fraction (LVEF) ≤ 45%), ESC EORP PPCM Registry, 51 countries, 2012–2018465 with 6-month echocardiogram
Participants
752 women
Outcome
LV recovery (LVEF ≥50%)
Follow-up
6 months

Performance

As reported in the abstract

Prediction of LV recovery at 6 months (ESC EORP PPCM Recovery Score)

Left ventricular (LV) recovery occurred

216 (46.5%)

Model discrimination, C-statistic

0.79 (95% CI 0.74-0.83)

Optimism-corrected C-statistic, internal validation

0.78 (95% CI 0.73-0.82)

Original publication

A novel score to predict left ventricular recovery in peripartum cardiomyopathy derived from the ESC EORP Peripartum Cardiomyopathy Registry. Eur Heart J. Published 29 January 2024. doi:10.1093/eurheartj/ehad888

Summarised from the published abstract; every number is checked against it