Acute cardiac care & resuscitation
A practical magnetic-resonance imaging score for outcome prediction in comatose cardiac arrest survivors
Authors' conclusion
A simplified, qualitative MRI score had excellent reliability and good discrimination for poor neurologic outcome.
Study context
- Population
- Adult comatose cardiac arrest survivors who underwent Magnetic Resonance Imaging (MRI)
- Participants
- 219 survivors
- Comparison
- Qualitative MRI hypoxic-ischemic brain injury (HIBI) scores for poor neurological outcome
- Outcome
- Discrimination (AUC) of poor neurological outcome (Cerebral Performance Category (CPC) 3-5)
- Follow-up
- Hospital discharge
Methodological detailsretrospective, single-centre, blinded raters
- Retrospective
- Single-centre
- Blinded raters
Performance
As reported in the abstract
AUC for poor outcome
| Test or model | AUC (95% CI) |
|---|---|
| Cortex | 0.84 (0.78-0.90) |
| Deep grey nuclei (DGN) | 0.83 (0.77-0.89) |
| Cortex-DGN | 0.83 (0.77-0.89) |
| Total | 0.83 (0.77-0.88) |
AUC (95% CI)
Cortex0.84 (0.78-0.90)
Deep grey nuclei (DGN)0.83 (0.77-0.89)
Cortex-DGN0.83 (0.77-0.89)
Total0.83 (0.77-0.88)
Further findings
| Outcome | Cortex | DGN | Cortex-DGN | Total |
|---|---|---|---|---|
| Inter-rater reliability (ICC) | ||||
| ICC (95% CI) | 0.92 (0.89-0.94) | 0.88 (0.80-0.92) | 0.94 (0.92-0.95) | 0.93 (0.91-0.95) |
Time to MRI
- Median time to MRI 96 h (IQR 81-110)
- 96
Original publication
A practical magnetic-resonance imaging score for outcome prediction in comatose cardiac arrest survivors. Resuscitation. Published 22 August 2024. doi:10.
Summarised from the published abstract; every number is checked against it