A Technology-Assisted Web Application for Consumer Access to a Nonprescription Statin Medication
Authors' conclusion
In this actual use study, a technology-assisted Web App allowed >90% of consumers to correctly self-select for statin use and achieve clinically important LDL-C reductions.
Study context
- Population
- Consumers without a medical background assessed for nonprescription statin eligibility; median age 63 years, 39.6% women, mean low-density lipoprotein cholesterol (LDL-C) 139.6 ± 28.3 mg/dL
- Participants
- 1,196 participants
- Outcome
- Concordance between Web App self-selection and clinician assessment of eligibility
Methodological detailssingle-group, 6-month
- Single-group
- 6-month
Main finding
As reported in the abstract
Concordance of Web App self-selection with clinician assessment
| Group | Initial self-selection concordant | Final use outcome concordant during treatment |
|---|---|---|
| Web App | 90.7% (95% CI: 88.9%-92.3%) | 98.1% (95% CI: 97.1%-98.8%) |
Web App
Initial self-selection concordant90.7% (95% CI: 88.9%-92.3%)
Final use outcome concordant during treatment98.1% (95% CI: 97.1%-98.8%)
Observational data: associations, not effects.
Further findings
Percent change in LDL-C
- Mean percent change in LDL-C
- −35.5% (95% CI: −36.6% to −34.3%)
Concordant final use outcome during treatment
- Concordant final use outcome
- 98.1% (95% CI: 97.1%-98.8%)
Safety
Serious adverse events
- Serious AEs, none related to study drug
- 27 (2.3%)
Original publication
A Technology-Assisted Web Application for Consumer Access to a Nonprescription Statin Medication. J Am Coll Cardiol. Published 8 April 2024. doi:10. 1016/ j. jacc. 2024. 03. 388
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