Prevention & lipids

A Technology-Assisted Web Application for Consumer Access to a Nonprescription Statin Medication

J Am Coll CardiolPublished Prospective actual use study

Authors' conclusion

In this actual use study, a technology-assisted Web App allowed >90% of consumers to correctly self-select for statin use and achieve clinically important LDL-C reductions.

Study context

Population
Consumers without a medical background assessed for nonprescription statin eligibility; median age 63 years, 39.6% women, mean low-density lipoprotein cholesterol (LDL-C) 139.6 ± 28.3 mg/dL
Participants
1,196 participants
Outcome
Concordance between Web App self-selection and clinician assessment of eligibility
Methodological detailssingle-group, 6-month
  • Single-group
  • 6-month

Main finding

As reported in the abstract

Concordance of Web App self-selection with clinician assessment
GroupInitial self-selection concordantFinal use outcome concordant during treatment
Web App90.7% (95% CI: 88.9%-92.3%)98.1% (95% CI: 97.1%-98.8%)

Web App

Initial self-selection concordant90.7% (95% CI: 88.9%-92.3%)
Final use outcome concordant during treatment98.1% (95% CI: 97.1%-98.8%)

Observational data: associations, not effects.

Further findings

Percent change in LDL-C

Mean percent change in LDL-C
−35.5% (95% CI: −36.6% to −34.3%)

Concordant final use outcome during treatment

Concordant final use outcome
98.1% (95% CI: 97.1%-98.8%)

Safety

Serious adverse events

Serious AEs, none related to study drug
27 (2.3%)

Original publication

A Technology-Assisted Web Application for Consumer Access to a Nonprescription Statin Medication. J Am Coll Cardiol. Published 8 April 2024. doi:10.1016/j.jacc.2024.03.388

Composed by AI from the published abstract and checked against it. How Briefs are made →

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