Abdominal Compared With Coronary Artery Calcification and Incident Cardiovascular Events and Mortality in Black Adults
Authors' conclusion
AAC is comparable to CAC in predicting cardiovascular events and all-cause mortality among Black adults, potentially valuable when CAC is absent.
Study context
- Population
- Black adults without CVD, JHS visit 2 (2005–2008), followed through 2016
- Participants
- 2,551 adults
- Exposure
- Abdominal aortic calcification (AAC) vs coronary artery calcium (CAC) for predicting CV events and mortality
- Outcome
- Incident CV events:
- MI
- Stroke
- HF
- All-cause mortality
- Follow-up
- 12.6 years
Main finding
As reported in the abstract
CV events, per 2-fold increase (adjusted)
Hazard ratio (95% CI)
CAC
1.10(1.06–1.13)
AAC
1.10(1.06–1.13)
Per 2-fold increase, as printed
- CV events observed
- 287 (11.3%)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| All-cause mortality, per 2-fold increase (adjusted)CAC | 1.04 (1.01–1.08) | |
| All-cause mortality, per 2-fold increase (adjusted)AAC | 1.05 (1.01–1.08) | |
| AAC in participants with 0 CAC (subgroup)CV events, per 2-fold increase | 1.07 (1.01–1.19) | |
| 0.512Hazard ratio (log scale) |
Net reclassification index
| Outcome | CAC | AAC |
|---|---|---|
| Incremental value added to pooled cohort equation (net reclassification index) | 0.17 (95% CI 0.08–0.23) | 0.15 (95% CI 0.07–0.29) |
- All-cause mortality, per 2-fold increase (adjusted) — Mortality cases observed
- 360 (14.1%)
- AAC in participants with 0 CAC (subgroup) — Participants with 0 CAC showing some AAC
- 45%
Incremental value added to pooled cohort equation (net reclassification index)
- Incremental value comparable
AAC in participants with 0 CAC (subgroup)
- Not associated with all-cause mortality
Original publication
Abdominal Compared With Coronary Artery Calcification and Incident Cardiovascular Events and Mortality in Black Adults. Circ Cardiovasc Imaging. Published 27 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →