Prevention & lipidsResearch article
Accelerated vascular ageing: an early prognostic signal for risk stratification and prevention
- Narrative review
Authors' conclusion
Despite a robust prognostic signal, clinical adoption has been constrained by fragmented biomarkers, heterogeneous measurement approaches, and absence of outcome-based decision pathways.
Main finding
As reported in the abstract
Prognostic value of accelerated vascular ageing biomarkers (arterial stiffness, central pressures, wave reflection indices)
- Biomarkers of arterial stiffness, central pressures and wave reflection consistently predict adverse outcomes independently of brachial BP, often preceding overt disease
- Durable modification of structural arterial stiffening by lifestyle and pharmacologic interventions remains limited
- Incremental value of composite vascular ageing metrics over pulse wave velocity remains uncertain
Original publication
Accelerated vascular ageing: an early prognostic signal for risk stratification and prevention. Eur J Prev Cardiol. Published 3 June 2026. doi:10.1093/eurjpc/zwag301
Summarised from the published abstract; every number is checked against it