Valvular & structural heart diseaseCohort study
Acceleration Time/Ejection Time Ratio Compared to Mean Gradient as a Predictor of Clinical Outcomes Post-TAVR
- Retrospective cohort study
Authors' conclusion
Post-TAVR AT/ET ≥0.35 can potentially predict clinical outcomes such as HFH.
Study context
- Population
- Patients >18 years undergoing transcatheter aortic valve replacement (TAVR), 2016–2020
- Participants
- 1,900 patients
- Exposure
- Aortic valve (AV) acceleration time (AT)/ejection time (ET) ≥ 0.35 vs AV AT/ET < 0.35 after TAVR
- Outcome
- HF hospitalization and mortality
- Follow-up
- 1 year
Main finding
As reported in the abstract
HF hospitalization
AT/ET ≥ 0.35 associated with increased 1-year HF hospitalization
P < 0.001
Observational data: associations, not effects.
Further findings
AT/ET ≥0.35 by valve type
P = 0.001
AV mean gradient >20 vs <20 mm Hg: 1-year HF hospitalization and mortality
- Comparable 1-year HF hospitalization
- P = 0.46
- Comparable mortality
Original publication
Acceleration Time/Ejection Time Ratio Compared to Mean Gradient as a Predictor of Clinical Outcomes Post-TAVR. JACC Cardiovasc Interv. Published 22 September 2025. doi:10.1016/j.jcin.2025.07.037
Summarised from the published abstract; every number is checked against it