Prevention & lipidsCohort study
Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease
- Retrospective cohort study
- UK Biobank
Authors' conclusion
Physical activity concentrated within 1 to 2 days was associated with similarly lower risk of cardiovascular outcomes to more evenly distributed activity.
Study context
- Population
- UK Biobank participants with a full week of accelerometer data, 2013–2015
- Participants
- 89,573 participants
- Exposure
- Active weekend warrior vs active regular vs inactive MVPA patterns
- Active WWn = 37,872
- Active regularn = 21,473
- Inactiven = 30,228reference
Main finding
As reported in the abstract
Incident AF, MI, HF, stroke (threshold ≥150 min/wk)
| Group | AF HR | MI HR | HF HR | Stroke HR |
|---|---|---|---|---|
| Active WW | 0.78 (95% CI 0.74-0.83) | 0.73 (95% CI 0.67-0.80) | 0.62 (95% CI 0.56-0.68) | 0.79 (95% CI 0.71-0.88) |
| Active regular | 0.81 (95% CI 0.74-0.88) | 0.65 (95% CI 0.57-0.74) | 0.64 (95% CI 0.56-0.73) | 0.83 (95% CI 0.72-0.97) |
| Inactive | 1.00 (95% CI 0.94-1.07) | 1.00 (95% CI 0.91-1.10) | 1.00 (95% CI 0.92-1.09) | 1.00 (95% CI 0.90-1.11) |
Observational data: associations, not effects.
Further findings
| Outcome | Active WW | Active regular | Inactive |
|---|---|---|---|
| Stroke at median threshold (≥230.4 min/wk MVPA) | |||
| Stroke HR | 0.89 (95% CI 0.79-1.02) | 0.87 (95% CI 0.74-1.02) | 1.00 (95% CI 0.90-1.11) |
Stroke at median threshold (≥230.4 min/wk MVPA)
- Findings consistent at median threshold; stroke associations no longer significant
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease. JAMA. Published 18 July 2023. doi:10.1001/jama.2023.10875
Summarised from the published abstract; every number is checked against it