Valvular & structural heart diseaseSecondary analysis
Accelerometer-Measured Physical Activity After Mitral Valve Surgery: An Analysis of the UK Mini Mitral Randomized Controlled Trial
- Secondary analysis of the UK Mini Mitral randomised controlled trial
- blinded outcome analysis
- Secondary analysis using a different primary end point
Wrist-worn triaxial accelerometer for 24 h over 7 days before surgery and at 6, 12, 18, 24, 38 and 52 weeks after surgery
Authors' conclusion
The data support an overall decline from baseline activity to 52 weeks in patients undergoing a sternotomy and an earlier recovery of physical activity after a minimally invasive thoracoscopically guided right minithoracotomy approach.
Study context
- Population
- Patients undergoing mitral valve repair in the UK Mini Mitral trial, with valid wrist-worn accelerometry datavalid accelerometry data
- Participants
- 230 patients
- Comparison
- Mini vs Sternotomy
- Minin = 115
- Sternotomyn = 115reference
Primary result
As reported in the abstract
Total activity counts
- 6 weeks
- mean difference 26 744 (95% CI 9085-44 403); P = 0.003
- 18 weeks
- mean difference 26 060 (95% CI 6971-45 149); P = 0.008
Further findings
| Outcome | mean difference (minutes per day) (95% CI) | P value | |
|---|---|---|---|
| Time in moderate-to-vigorous physical activity — Mini vs Sternotomy · 6 weeks | 15 (5.7–24) | P = 0.001 | |
| Time in moderate-to-vigorous physical activity — Mini vs Sternotomy · 18 weeks | 9.9 (0.31–20) | P = 0.043 | |
| −100102030Difference, minutes per day (linear scale) |
Sedentary time and light physical activity
- Significantly lower sedentary time with Mini (at 12, 18 and 24 weeks)
- More time in light physical activity with Mini (at 18 weeks)
Sleep duration and sleep efficiency
- No differences in sleep duration between arms at any time point
- Higher sleep efficiency with Mini at 12 weeks
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Accelerometer-Measured Physical Activity After Mitral Valve Surgery: An Analysis of the UK Mini Mitral Randomized Controlled Trial. Circulation. Published 5 September 2025. doi:10.1161/circulationaha.125.074651
Summarised from the published abstract; every number is checked against it