Coronary disease & ACSCohort study
Acute Coronary Syndrome Risk Prediction Using Portable Cable-Free Electrocardiogram (ECG) Device Combined With Clinical Risk Assessment
- prospective single-center study
- consecutive emergency department patients
- learning set and test set
Authors' conclusion
An algorithm combining clinical risk factors, symptoms, and ECG recording using hand-held cable-free device provides clinically meaningful ACS risk stratification. If fully integrated into a personal device, it may help support early self-triage decisions and reduce patient-related prehospital delays.
Study context
- Population
- Emergency department patients with chest painenrolled, 184 patients with complete data were analyzed · learning set 96 · test set 88 · asymptomatic postevent reference portable ECG obtained 9 to 12 months later 98
- Participants
- 212 patients
- Exposure
- Algorithm performance was evaluated using receiver operating characteristic curve analysis and compared with human consensus interpretation of 12-lead ECG plus PER and symptom risk (SR) information
Main finding
As reported in the abstract
Algorithm ACS prediction, area under the curve
single portable ECG
0.865
with postevent reference comparison
0.929
Observational data: associations, not effects.
Further findings
False-positive rate
| Outcome | Algorithm | Human consensus |
|---|---|---|
| False-positive rate at matched sensitivity, single portable ECG | 0.527 | 0.458 |
| False-positive rate at matched sensitivity, using reference comparison | 0.198 | 0.556 |
- False-positive rate at matched sensitivity, single portable ECG: P = 0.709
- False-positive rate at matched sensitivity, using reference comparison: P = 0.004
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Acute Coronary Syndrome Risk Prediction Using Portable Cable-Free ECG Device Combined With Clinical Risk Assessment. JACC Adv. Published 21 May 2026. doi:10.1016/j.jacadv.2026.102827
Summarised from the published abstract; every number is checked against it