Arrhythmias & electrophysiologyCohort study
Acute post-procedural inducibility is a poor predictor of clinical outcomes in high-risk patients (PAINESD > 17) undergoing scar-related ventricular tachycardia ablation
- Retrospective cohort study
- single-centre
Authors' conclusion
The results of post-ablation PVS do not significantly correlate with long-term outcomes in high-risk (PAINESD > 17) VT ablation patients.
Study context
- Population
- High-risk patients (PAINESD > 17) undergoing scar-related ventricular tachycardia (VT) ablation, July 2010–July 2022of 1677 VT ablation cases
- Participants
- 123 patients
- Exposure
- Post-ablation programmed ventricular stimulation (PVS) response: Group A vs Group C
- Group Bn = 13
- Outcome
- Composite of:
- Death
- Durable LV assist device placement
- Cardiac transplant
- Follow-up
- Median 19 months (IQR 4-43 months)
Main finding
As reported in the abstract
Composite of:
- Death
- Durable LVAD placement
- Cardiac transplant
Patients with the composite primary endpoint (all groups)
82 (66.7%)
No difference between Groups A and C: HR 1.21 (0.94-1.57)
P = 0.145
Observational data: associations, not effects.
Secondary outcomes
VT recurrence
- No difference between Groups A and C: HR 1.18 (0.91-1.54)
- P = 0.210
- competing risk analysis
- persisted after multivariate adjustments
Original publication
Acute post-procedural inducibility is a poor predictor of clinical outcomes in high-risk patients (PAINESD > 17) undergoing scar-related ventricular tachycardia ablation. Europace. Published 20 July 2024. doi:10.1093/europace/euae185
Summarised from the published abstract; every number is checked against it