Coronary disease & ACSCohort study
Adjunctive Imaging and Physiology During Percutaneous Coronary Intervention
- Retrospective cohort study
- Medicare fee-for-service claims
- multivariable Cox regression
Authors' conclusion
The dual use of IVI and IP has marginally increased and was associated with lower MACE and long-term costs compared with angiography alone.
Study context
- Population
- Medicare beneficiaries ≥65 years with a first percutaneous coronary intervention (PCI), US, 2016–2023included in analysis
- Participants
- 1,587,532 beneficiaries
- Exposure
- Dual intravascular imaging (IVI) and invasive physiology (IP) vs angiography alone during PCI
- Outcome
- Major adverse cardiovascular events (MACE):
- MI
- Repeat revascularization
- All-cause death
- Follow-up
- 2 years
Main finding
MACE
Adjusted hazard ratio
0.87
95% CI 0.85–0.89
P < 0.0001
Dual IVI and IP vs Angiography alone
adjusted HR 0.87 (95% CI 0.85–0.89); P < 0.0001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Dual IVI and IP | IVI | IP | Angiography alone |
|---|---|---|---|---|
| Use during PCI, overall 2016–2023 | 2.5% | 15% | 7% | Not reported in the abstract |
| Use during PCI by 2023 · about | 4.7% | 30% | Not reported in the abstract | Not reported in the abstract |
- Use during PCI, overall 2016–2023: about; of all 2,538,154 PCIs
Costs
- Higher upfront procedural costs but lower long-term costs with any use of IVI and/or IP
Original publication
Adjunctive Imaging and Physiology During Percutaneous Coronary Intervention. JACC Cardiovasc Interv. Published 12 January 2026. doi:10.1016/j.jcin.2025.09.047
Summarised from the published abstract; every number is checked against it