Coronary disease & ACSMeta-analysis
Advanced Analyses of Coronary Computed Tomography Angiography to Predict Future Cardiac Events
- Systematic review and meta-analysis
Authors' conclusion
Advanced coronary CTA-based analyses show consistent association to the occurrence of MACE, suggesting their potential for refining cardiovascular risk stratification on top of conventional clinical risk assessment.
Study context
- Population
- Studies reporting coronary computed tomographic angiography (CTA)-based advanced analyses predicting major adverse cardiovascular events (MACE)
- Participants
- 58,123 participants · 52 studies
- Comparison
- Advanced coronary CTA-based analyses for prediction of MACE
- Outcome
- Pooled HR of advanced coronary CTA-based analyses for prediction of MACE
Pooled result
As reported in the abstract
MACE
Hazard ratio (95% CI)P value
CT-FFR
6.14(3.75–10.05)
P < 0.01High-risk plaque
4.05(3.16–5.18)
P < 0.01Original publication
Advanced Analyses of Coronary Computed Tomography Angiography to Predict Future Cardiac Events. JACC Cardiovasc Imaging. Published 5 August 2025. doi:10.1016/j.jcmg.2025.05.017
Summarised from the published abstract; every number is checked against it