Heart failure & cardiomyopathiesCohort study
Advanced Heart Failure Characteristics and Outcomes in Commercially Insured U.S. Adults
- Retrospective cohort study
- administrative claims database
Authors' conclusion
In U.S. adults with advanced HF, variation in outcomes and use of advanced therapies exist by age, sex, and race/ethnicity.
Study context
- Population
- Commercially insured US adults with advanced heart failure (HF) (2 HF hospitalizations plus 1 additional sign of advanced HF in 12 months), OptumLabs Data Warehouse, 2009–2019
- Participants
- 60,197 participants
Main finding
As reported in the abstract
Survival with advanced HF
Median survival
2.0 years (IQR: 0.4-5.5 years)
Adjusted mortality higher in older, male, non-Hispanic White and rural patients
P < 0.05 for all
Observational data: associations, not effects.
Further findings
Baseline characteristics
- Mean age
- 73 years
- Men
- 51.5%
- Non-Hispanic White
- 64.3%
- Asian
- 1.9%
- Black
- 21.2%
- Hispanic
- 8.2%
Use of advanced therapies
- Advanced therapies used less in older patients and women
- P < 0.05 for both
- Black vs White patients: more likely to be treated with LV assist device
- P = 0.010
- Black vs White patients: less likely to receive heart transplant
- P = 0.034
Original publication
Advanced Heart Failure Characteristics and Outcomes in Commercially Insured U.S. Adults. JACC Heart Fail. Published 16 August 2023. doi:10.1016/j.jchf.2023.06.029
Summarised from the published abstract; every number is checked against it