Heart failure & cardiomyopathies

Advanced Heart Failure Characteristics and Outcomes in Commercially Insured U.S. Adults

JACC Heart FailPublished Retrospective cohort study

Authors' conclusion

In U.S. adults with advanced HF, variation in outcomes and use of advanced therapies exist by age, sex, and race/ethnicity.

Study context

Population
Commercially insured US adults with advanced heart failure (HF) (2 HF hospitalizations plus 1 additional sign of advanced HF in 12 months), OptumLabs Data Warehouse, 2009–2019
Participants
60,197 participants
Outcome
Survival with advanced HF
Methodological detailsadministrative claims database
  • Administrative claims database

Main finding

As reported in the abstract

Median survival
2.0 years (IQR: 0.4-5.5 years)
Adjusted mortality higher in older, male, non-Hispanic White and rural patients
P < 0.05 for all

Observational data: associations, not effects.

Further findings

Baseline characteristics

Mean age
73 years
Men
51.5%
Non-Hispanic White
64.3%
Asian
1.9%
Black
21.2%
Hispanic
8.2%

Use of advanced therapies

Advanced therapies used less in older patients and women
P < 0.05 for both
Black vs White patients: more likely to be treated with LV assist device
P = 0.010
Black vs White patients: less likely to receive heart transplant
P = 0.034

Original publication

Advanced Heart Failure Characteristics and Outcomes in Commercially Insured U.S. Adults. JACC Heart Fail. Published 16 August 2023. doi:10.1016/j.jchf.2023.06.029

Composed by AI from the published abstract and checked against it. How Briefs are made →

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