Prevention & lipidsResearch article
Adverse pregnancy outcomes and long-term cardiovascular risk: lifelong connections
- Narrative review
Authors' conclusion
Recognizing pregnancy complications as indicators of underlying cardiovascular vulnerability offers an opportunity to shift prevention upstream and promote lifelong cardiovascular health for women.
Study context
- Population
- Women with adverse pregnancy outcomes (hypertensive disorders of pregnancy, gestational diabetes, pre-term birth, small-for-gestational-age birth, pregnancy loss)
Main finding
As reported in the abstract
Long-term CV risk after adverse pregnancy outcomes (APOs)
- Adverse pregnancy outcomes (APOs) (hypertensive disorders of pregnancy, gestational DM, pre-term birth, small-for-gestational-age birth, pregnancy loss) are early markers of cardiometabolic dysfunction identifying women at increased risk of CAD, HF, stroke, CKD and premature CV mortality
- Early post-partum persistent hypertension, adverse cardiac remodelling and metabolic abnormalities mediate much of the long-term excess CV risk
Original publication
Adverse pregnancy outcomes and long-term cardiovascular risk: lifelong connections. Eur Heart J. Published 1 September 2026. doi:10.1093/eurheartj/ehag654
Summarised from the published abstract; every number is checked against it