Randomised controlled trial

Aerobic, resistance, or combined exercise training and cardiovascular risk profile in overweight or obese adults: the CardioRACE trial

Eur Heart JPublished

  • Randomised controlled trial

Authors' conclusion

In adults with overweight or obesity, aerobic exercise alone or combined resistance plus aerobic exercise, but not resistance exercise alone, improved composite CVD risk profile compared with the control.

Study context

Population
Adults aged 35–70 years with overweight or obesity and elevated BP381 (94%) completed 1-year follow-up
Participants
406 adults
Comparison
Resistance, aerobic or combined exercise vs no-exercise control
  • Resistancen = 102
  • Aerobicn = 101
  • Combinationn = 101
  • Controln = 102reference
Primary endpoint
Change in standardized composite Z-score of SBP, LDL cholesterol, fasting glucose and per cent body fat (decrease = improved CVD risk profile)
Follow-up
1 year

Primary result

As reported in the abstract

Each group vs controlMean difference (95% CI)P value
Aerobic
−0.15(−0.27 to −0.04)
P = 0.01
Combination
−0.16(−0.27 to −0.04)
P = 0.009
Resistance
−0.02(−0.14 to 0.09)
P = 0.69

Further findings

Individual cardiovascular disease (CVD) risk factors (per cent body fat, SBP, low-density lipoprotein (LDL) cholesterol, fasting glucose) · 1 year

Only per cent body fat decreased in all three exercise groups vs control; SBP, LDL cholesterol and fasting glucose did not decrease in any exercise group

Original publication

Aerobic, resistance, or combined exercise training and cardiovascular risk profile in overweight or obese adults: the CardioRACE trial. Eur Heart J. Published 17 January 2024. doi:10.1093/eurheartj/ehad827

Summarised from the published abstract; every number is checked against it