Heart failure & cardiomyopathiesResearch article
Albuminuria as a Diagnostic Criterion and a Therapeutic Target in Heart Failure and Other Cardiovascular Disease
- Narrative review
Study context
- Population
- Patients at risk of kidney and heart disease (chronic kidney disease (CKD), heart failure (HF) and other cardiovascular disease (CVD))
Main finding
As reported in the abstract
Urine albumin-to-creatinine ratio (uACR) as diagnostic and prognostic marker
- Urine albumin-to-creatinine ratio (uACR) recognised as a diagnostic marker for CKD and a prognostic marker for CKD progression, HF and CVD outcomes; albuminuria changes accepted as a surrogate outcome for kidney and CV endpoints
- In trials of guideline-directed medical therapies, uACR reductions accompanied by risk reductions for CV, HF and other CKD outcomes
- uACR not routinely measured in patients at risk of kidney and heart disease
Original publication
Albuminuria as a Diagnostic Criterion and a Therapeutic Target in Heart Failure and Other Cardiovascular Disease. Eur J Heart Fail. Published 27 May 2025. doi:10.1002/ejhf.3683
Summarised from the published abstract; every number is checked against it