Valvular & structural heart diseaseCohort study

Alternative pacing strategies after transcatheter tricuspid valve interventions: Procedural challenges and lessons learned

Heart RhythmPublished

  • retrospective
  • single institution
  • consecutive patients

Authors' conclusion

Alternative nontransvalvular pacing strategies may be feasible and safe in patients who require pacing after TTVI. Preprocedural planning with a multidisciplinary approach can help optimize procedural success. Further studies and longer-term follow-up are warranted.

Study context

Population
Patients undergoing transcatheter tricuspid valve intervention (TTVI), including transcatheter edge-to-edge repair (TEER) or transcatheter tricuspid valve replacement (TTVR), evaluated for new pacemaker indications and pacing strategypatients who underwent TTVI, 34 (25%) excluded for preexisting pacemaker, 15 of 103 (15%) developed a pacing indication · TTVR 69 · TEER 68
Participants
137 patients
Exposure
Nontransvalvular pacing strategies after TTVI
  • TEERn = 68
  • TTVRn = 69

Main finding

As reported in the abstract

Indication for pacing after TTVI
Patients without preexisting pacemaker who developed a pacing indication
15 of 103 patients (15%)

Observational data: associations, not effects.

Further findings

Success of alternative pacing strategy after TEER · initial attempt
50% successful (2 of 4) · coronary sinus (CS) lead placement · leadless pacemaker (LP) attempt unsuccessful (0 of 1)
Success of alternative pacing strategy after TTVR · initial attempt
75% successful (6 of 8) · CS lead placement · LP placement 100% successful (2 of 2)

Procedural limitations

CS lead placement was limited by CS anatomy, whereas LP placement was limited by TTVR interaction
A transvenous pacemaker was successfully placed if needed

Safety

Pacemaker device-related adverse events · peri-procedurally or at 1-year follow-up

No pacemaker device-related adverse event occurred in any patient

Original publication

Alternative pacing strategies after transcatheter tricuspid valve interventions: Procedural challenges and lessons learned. Heart Rhythm. Published 10 October 2025. doi:10.1016/j.hrthm.2025.10.013

Summarised from the published abstract; every number is checked against it