Arrhythmias & electrophysiologyCohort study

An integrated approach to radiofrequency ablation of para-Hisian accessory pathways in paediatric patients

Heart RhythmPublished

  • single-centre retrospective study

Authors' conclusion

Our integrated ablation strategy effectively addresses the unique challenges of paediatric PHAP ablation, achieving durable efficacy and high procedural safety.

Study context

Population
Paediatric patients undergoing para-Hisian accessory pathway (PHAP) ablation, January 2023 to September 2025paediatric patients (median age 10 years)
Participants
41 patients

Main finding

As reported in the abstract

Acute success and permanent complications
  • All 41 cases achieved acute success with no permanent complications

Observational data: associations, not effects.

Further findings

Recurrence among manifest pathways, pace-mapping added to activation mapping vs not

  • Recurrence among manifest pathways, pace-mapping added to activation mapping vs not: hypothesis-generating trend that did not reach statistical significance (P = .056)

Mechanical pathway block during mapping

Mechanical pathway block during mapping
43.9% (18/41)

Stable ablation with subvalvular retroflexion

Subvalvular retroflexion enabled stable ablation
90.2% (37/41)
patients <10 kg required supravalvular approaches
3
concealed pathway successfully ablated from the non-coronary cusp
one

Recurrence · median 19-month follow-up

Recurrence
7.4% (3/41)

Predictors of recurrence (univariate analysis)

Higher recurrence risk for pathways with a W-pattern in lead V1 and for those in the superior mid-septal region
  • univariate analysis

Original publication

An integrated approach to radiofrequency ablation of para-Hisian accessory pathways in paediatric patients. Heart Rhythm. Published 8 January 2026. doi:10.1016/j.hrthm.2026.01.002

Summarised from the published abstract; every number is checked against it