Arrhythmias & electrophysiologyCohort study
Anatomical-guided third-generation laser balloon ablation for the treatment of paroxysmal atrial fibrillation assessed by continuous rhythm monitoring: results from a multicentre prospective study
- Prospective cohort study
- multicentre
- single-group
Authors' conclusion
Anatomical-guided LB3 ablation for paroxysmal AF is a safe and effective approach, providing excellent clinical outcomes as assessed by ICM over nearly 3 years of follow-up.
Study context
- Population
- Paroxysmal AF patients undergoing laser balloon (LB3) ablation, 4 Italian centresof 257 screened
- Participants
- 204 patients
- Outcome
- Freedom from any atrial tachyarrhythmia recurrence after the blanking period, assessed with implantable cardiac monitors
Main finding
As reported in the abstract
Freedom from any ATa recurrence after the BP (ICM)
Freedom from arrhythmia recurrences at 1 year
84.8%
Freedom from arrhythmia recurrences at 2 years
80.4%
Freedom from arrhythmia recurrences at 3 years
76.0%
Observational data: associations, not effects.
Further findings
Atrial tachyarrhythmia (ATa) burden ≥ 5%
- ATa burden ≥ 5% at 1 year
- 2.5%
- ATa burden ≥ 5% at 2 years
- 4.4%
- ATa burden ≥ 5% at 3 years
- 5.4%
Independent predictors of recurrences
- Relapses during the blanking period (BP), HR
- 2.182 (P = 0.032)
- Left atrial dilation, HR
- 1.964 (P = 0.048)
Original publication
Anatomical-guided third-generation laser balloon ablation for the treatment of paroxysmal atrial fibrillation assessed by continuous rhythm monitoring: results from a multicentre prospective study. Europace. Published 7 November 2024. doi:10.1093/europace/euae263
Summarised from the published abstract; every number is checked against it