Angiography-derived assessment of coronary microcirculatory resistance in patients with suspected myocardial ischaemia and non-obstructive coronary arteries
Authors' conclusion
Evaluating coronary microcirculatory resistance in patients with INOCA syndrome using cAngio-IMR is feasible and accurate.
Study context
- Population
- Patients with clinically indicated coronary angiography for suspected myocardial ischaemia and angiographically normal or non-obstructive coronary arteries (ischaemia with non-obstructive coronary arteries (INOCA))104 analysed (108 vessels)
- Comparison
- Angiography-derived IMR vs thermodilution-derived IMR
- Outcome
- Diagnostic yield of angio-IMR vs thermo-IMR
Methodological detailsinvestigator-driven, prospective, blinded, independent blinded physiology core laboratory, 67% female, Obstructive epicardial disease ruled out angiographically (diameter stenosis <50%) and physiologically (FFR >0.80) in all cases
- Investigator-driven
- Prospective
- Blinded
- Independent blinded physiology core laboratory
- 67% female
- Obstructive epicardial disease ruled out angiographically (diameter stenosis <50%) and physiologically (FFR >0.80) in all cases
Performance
IMR
Median difference
−0.31
95% CI −1.53 to 1.00
P = 0.654
By group
cAngio-IMR vs thermo-IMR
median difference −0.31 (95% CI −1.53 to 1.00); P = 0.654
As reported in the abstract
- Pearson correlation P
- P < 0.001
- AUC P
- P < 0.001
Original publication
Angiography-derived assessment of coronary microcirculatory resistance in patients with suspected myocardial ischaemia and non-obstructive coronary arteries. EuroIntervention. Published 3 April 2023. doi:10.
Summarised from the published abstract; every number is checked against it