Arrhythmias & electrophysiology
Antegrade approach for left ventricular tachyarrhythmia in patients with previous transcatheter edge-to-edge mitral valve repair
Authors' conclusion
An antegrade approach for LVT ablation is feasible and safe despite previous MV-TEER.
Study context
- Population
- Patients with drug-refractory ventricular tachycardia (VT) and previous mitral valve transcatheter edge-to-edge repair (MV-TEER)
- Participants
- 34 patients
- Outcome
- Feasibility, safety and clinical effectiveness of antegrade transseptal catheter ablation for LV tachyarrhythmia
Methodological detailsmulticentre, single-arm
- Multicentre
- Single-arm
Main finding
As reported in the abstract
Feasibility of antegrade transseptal ablation
- Catheter manipulation through septal and lateral mitral openings feasible in all cases, regardless of clip number
- Complete LV mapping achieved without restrictions
Observational data: associations, not effects.
Further findings
VT recurrence · median follow-up 32 months (IQR 17.5-48.5)
- VT recurrence
- 4 patients (11.8%)
Safety
Clip dislocation (transthoracic echocardiography) · first postprocedural day
- Clip dislocations
- 0
Original publication
Antegrade approach for left ventricular tachyarrhythmia in patients with previous transcatheter edge-to-edge mitral valve repair. Heart Rhythm. Published 9 October 2025. doi:10.
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