Aortic & peripheral vascular disease
Aortic sodium [ 18 F]fluoride uptake following endovascular aneurysm repair
Authors' conclusion
EVAR is associated with a reduction in AMA within the stented aortic segment.
Study context
- Population
- Patients with infrarenal AAA undergoing EVAR per guideline-directed size thresholds (age 76±6 years; mean aortic diameter 57±2 mm)
- Participants
- 10 patients
- Exposure
- Aortic sodium [18F]fluoride uptake before vs after EVAR
- Outcome
- Change in regional aortic sodium [18F]fluoride uptake (aortic microcalcification activity, AMA)
- Follow-up
- Mean 62±21 months after EVAR
Methodological detailspreliminary proof-of-concept
- Preliminary proof-of-concept
Main finding
As reported in the abstract
Change in AMA after EVAR (ΔAMA)
- Suprarenal; reduction
- ΔAMA 0.62; P = 0.03
- Aneurysm neck; reduction
- ΔAMA 0.72; P = 0.02
- Aneurysm body; reduction
- ΔAMA 0.69; P = 0.02
- Thoracic aorta; unchanged
- ΔAMA 0.11; P = 0.41
Observational data: associations, not effects.
Further findings
Pre-EVAR aortic microcalcification activity (AMA), abdominal vs thoracic aorta · before EVAR
- Abdominal aortic AMA vs thoracic aorta AMA
- 1.88 vs 1.2; p<0.001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Aortic sodium [ 18 F]fluoride uptake following endovascular aneurysm repair. Heart. Published 10 May 2023. doi:10.
Summarised from the published abstract; every number is checked against it