QFR-Based Virtual Percutaneous Coronary Intervention (PCI) or Conventional Angiography to Guide PCI: The AQVA Trial
Primary resultResult — go to the resultAbsolute difference 8.5%Authors' conclusion
The AQVA trial demonstrated the superiority of QFR-based virtual PCI over angiography-based PCI with regard to post-PCI optimal physiological results.
Study context
- Population
- Patients undergoing PCI
- Participants
- 300 patients356 study vessels
- Comparison
- Quantitative flow ratio (QFR)-based virtual PCI vs angiography-based PCI
- Primary endpoint
- Rate of study vessels with suboptimal post-PCI QFR (<0.90)
Methodological detailsinvestigator-initiated, parallel-group
- Investigator-initiated
- Parallel-group
Primary result
As reported in the abstract
Absolute difference
8.5%
P = 0.009
Events by treatment group
Secondary outcomes
Procedure duration, stent length/lesion, stent number/patient
- No significant differences; stent length/lesion numerically lower with virtual PCI
- P = 0.06
- Stent number/patient numerically lower with virtual PCI
- P = 0.08
- Procedure length higher with virtual PCI
- P = 0.06
Original publication
QFR-Based Virtual PCI or Conventional Angiography to Guide PCI: The AQVA Trial. JACC Cardiovasc Interv. Published 8 March 2023. doi:10.
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