Pulmonary vascular disease & thromboembolismCohort study

Arterial cardiovascular disease risk after venous thromboembolism in young adults: a Danish nationwide cohort study

Eur J Prev CardiolPublished

  • Nationwide cohort study
  • age- and sex-matched (1:5) comparison cohort

Authors' conclusion

Young adults with VTE had an elevated risk of CVD compared with persons in an age- and sex-matched comparison cohort.

Study context

Population
Young adults (≤40 years) with venous thromboembolism (VTE), Denmark, 1996–2021
Participants
15,810 vs 79,050
Exposure
VTE vs Comparison
  • VTEn = 15,810
  • Comparisonn = 79,050reference
Outcome
Cardiovascular disease (CVD) (MI and ischemic stroke)
Follow-up
0-1-, 0-5- and 0-10-year windows

Main finding

As reported in the abstract

VTE vs ComparisonAdjusted hazard ratio (95% CI)
0-1-year window
7.4(4.3–12.8)
0-5-year window
3.8(3.0–4.9)
0-10-year window
3.1(2.6–3.6)

Observational data: associations, not effects.

Further findings

MI and ischemic stroke separately; strata by sex, age, VTE-provoking risk factors, calendar year

Similar findings

Original publication

Arterial cardiovascular disease risk after venous thromboembolism in young adults: a Danish nationwide cohort study. Eur J Prev Cardiol. Published 22 November 2025. doi:10.1093/eurjpc/zwaf747

Summarised from the published abstract; every number is checked against it