Arrhythmias & electrophysiologyDiagnostic or prognostic study

Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography

Nat MedPublished

  • Diagnostic accuracy study

Authors' conclusion

We conclude that the DeepRhythmAI model has excellent negative predictive value for critical arrhythmias, substantially reducing false-negative findings, but at a modest cost of increased false-positive findings.

Study context

Population
Ambulatory electrocardiogram (ECG) recordings (mean duration 14 ± 10 days)
Participants
14,606 ECG recordings
Comparison
Technicians vs DeepRhythmAI
  • Techniciansn = 167reference
Outcome
Sensitivity for identification of critical arrhythmias

Performance

Critical arrhythmias

Relative risk

14.1

95% CI 10.4–19.0

By group

DeepRhythmAI

98.6% (95% CI 97.7-99.4)

Mean sensitivity · False-negative findings 3.2/1,000 patients

Technicians

80.3% (95% CI 77.3-83.3%)

Mean sensitivity · False-negative findings 44.3/1,000 patients

Technicians vs DeepRhythmAI
RR 14.1 (95% CI 10.4–19.0)

As reported in the abstract

Safety

False-positive event rate

Original publication

Artificial intelligence for direct-to-physician reporting of ambulatory electrocardiography. Nat Med. Published 10 February 2025. doi:10.1038/s41591-025-03516-x

Summarised from the published abstract; every number is checked against it