Coronary disease & ACSCross-sectional study

Aspirin for Secondary Prevention of Cardiovascular Disease in 51 Low-, Middle-, and High-Income Countries

JAMAPublished

  • Cross-sectional study
  • pooled individual participant data
  • nationally representative health surveys

Authors' conclusion

Worldwide, aspirin is underused in secondary prevention, particularly in low-income countries.

Study context

Population
Nonpregnant adults aged 40 to 69 years in 51 low-, middle- and high-income countries, national health surveys 2013–202010,589 with cardiovascular disease (CVD) history
Participants
124,505 adults
Exposure
Aspirin use for secondary prevention by country income group
Outcome
Self-reported use of aspirin for secondary prevention of CVD

Main finding

As reported in the abstract

Aspirin use among individuals with a history of CVD
Overall pooled aspirin use for secondary prevention
40.3% (95% CI, 37.6%-43.0%)

Observational data: associations, not effects.

Further findings

Self-reported history of CVD

Prevalence of self-reported CVD history
8.1% [95% CI, 7.6%-8.6%]
  • 10 589 individuals

Original publication

Aspirin for Secondary Prevention of Cardiovascular Disease in 51 Low-, Middle-, and High-Income Countries. JAMA. Published 22 August 2023. doi:10.1001/jama.2023.12905

Summarised from the published abstract; every number is checked against it