Assessment of the Relevant Field of View of Unipolar Electrodes Using In Vivo Imaging

Authors' conclusion

Clinical evaluation of 1-mm and 460-μm electrodes suggests a larger FOV than preclinical investigations. This quantifies a larger scale across which myocardial viability can influence unipolar electrogram signals observed during ablation procedures and suggests that smaller electrodes can improve spatial sampling density but do not necessarily provide a distinctly more localized characterization of the electrophysiologic properties of the tissue. LGE-CMR best predicted unipolar voltage, whereas CCT-ECV performed less well. Correlations were lower than expected, indicating the need for electrophysiologic assessment alongside comprehensive imaging.