Arrhythmias & electrophysiologyCohort study
Association between baseline adherence to a healthy lifestyle with ischemic and major cardiovascular events in patients with atrial fibrillation
- Cohort study
Authors' conclusion
High baseline adherence to a healthy lifestyle reduced the risk of ischemic and major cardiovascular events in AF patients.
Study context
- Population
- Atrial fibrillation (AF) patients starting oral anticoagulation (OAC) between January 2016 and November 2021
- Participants
- 3,266 patients
- Exposure
- High or moderate vs poor baseline adherence to a healthy lifestyle
- Highn = 906
- Outcome
- Composite of ischemic events
- Follow-up
- 2-years follow-up
Main finding
As reported in the abstract
Composite ischemic events
Each group vs poorEstimate (95% CI)P value
Moderate
IRR 0.61(0.46–0.80)
High
IRR 0.59(0.42–0.81)
Highadjusted for OAC type
aHR 0.58(0.42–0.79)
P < 0.001Highadjusted for additional risk factors
aHR 0.59(0.42–0.81)
P = 0.001Observational data: associations, not effects.
Secondary outcomes
MACE; ischemic stroke/TIA/systemic embolism; competing risk analyses
- Similar results were observed
Original publication
Association between baseline adherence to a healthy lifestyle with ischemic and major cardiovascular events in patients with atrial fibrillation. Eur J Prev Cardiol. Published 14 May 2025. doi:10.1093/eurjpc/zwaf287
Summarised from the published abstract; every number is checked against it