Acute cardiac care & resuscitationCohort study
Association Between Chest Compression Pause Duration and Survival After Pediatric In-Hospital Cardiac Arrest
- Cohort study
- multicentre
Authors' conclusion
Each 5-second increment in longest CC pause duration during pediatric in-hospital cardiac arrest was associated with lower chance of survival with favorable neurological outcome, survival to hospital discharge, and return of spontaneous circulation.
Study context
- Population
- Index pediatric in-hospital cardiac arrests in pediRES-Q, July 2015 – December 2021
- Participants
- 562 index in-hospital cardiac arrests
- Exposure
- Longest chest compression (CC) pause duration
- Outcome
- Survival with favorable neurological outcome:
- Pediatric Cerebral Performance Category ≤3
- No change from baseline
Main finding
Survival with favorable neurological outcome
Adjusted risk ratio
0.97
95% CI 0.95–0.99
P = 0.02
Each 5-second increment in longest CC pause, as printed
As reported in the abstract
- Median longest CC pause per event
- 29.8 seconds (11.5, 63.1)
Observational data: associations, not effects.
Secondary outcomes
Survival to hospital discharge
| Comparison | adjusted risk ratio (95% CI) | P value | |
|---|---|---|---|
| Longest CC pause duration | 0.98 (0.96–0.99) | P = 0.01 | |
| 0.512Adjusted risk ratio (log scale) |
Return of spontaneous circulation
| Comparison | adjusted risk ratio (95% CI) | P value | |
|---|---|---|---|
| Longest CC pause duration | 0.93 (0.91–0.94) | P < 0.001 | |
| 0.512Adjusted risk ratio (log scale) |
Any pause >10 s or >20 s; number of CC pauses >10 s and >20 s (secondary exposures)
- Each significantly associated with adjusted risk ratio of return of spontaneous circulation, but not survival or neurological outcomes
Original publication
Summarised from the published abstract; every number is checked against it