Heart failure & cardiomyopathiesCohort study
Association between Life’s Essential 8 and risk of heart failure: findings from the Kailuan study
- Prospective cohort study
Authors' conclusion
LE8 was inversely associated with HF risk. Individuals with initially low LE8 levels experienced a reversal in HF risk upon improvement.
Study context
- Population
- Adults without prior heart failure (HF), Kailuan community461 HF events
- Participants
- 35,896 adults
- Exposure
- LE8 trajectories, status and annual change rate and risk of HF
- Outcome
- Incident HF
Main finding
HF
Hazard ratio
0.43
95% CI 0.34–0.55
Moderate-increasing vs Moderate-decreasing
HR 0.43 (95% CI 0.34–0.55)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Prediction of HF (C-index)
- LE8 trajectory more accurate than LE8 status in predicting HF risk
Original publication
Association between Life’s Essential 8 and risk of heart failure: findings from the Kailuan study. Eur J Prev Cardiol. Published 5 February 2025. doi:10.1093/eurjpc/zwaf024
Summarised from the published abstract; every number is checked against it