Heart failure & cardiomyopathies
Association of Body Mass Index (BMI) with Adherence and Outcome in Heart Failure Patients Treated with Wearable Cardioverter Defibrillator
Authors' conclusion
Obese patients exhibited significantly greater improvement in LVEF, which was associated with reduced mortality.
Study context
- Population
- Heart failure (HF) patients treated with a wearable cardioverter-defibrillator (WCD)
- Participants
- 1,003 patients
- Exposure
- BMI <25 and BMI 25-30 vs BMI >30 kg/m²
- BMI < 25n = 348
- BMI 25-30n = 383
- BMI > 30n = 272reference
- Outcome
- LVEF
- Follow-up
- 3 month
Methodological detailsmulticentre international registry, consecutive series, Retrospective data collection
- Multicentre international registry
- Consecutive series
- Retrospective data collection
Main finding
As reported in the abstract
BMI < 25 vs BMI > 30: P = 0.017 · BMI 25-30 vs BMI > 30: P = 0.635
Observational data: associations, not effects.
Further findings
CV rehospitalization — BMI 25-30 vs BMI > 30
P = 0.048
Mortality · 2 year follow-up — BMI < 25 vs BMI > 30
P = 0.029
| Outcome | BMI < 25 | BMI 25-30 | BMI > 30 | P value |
|---|---|---|---|---|
| ICD implantation | — not stated in the abstract | — not stated in the abstract | 36.8% | |
| CV rehospitalizationBMI < 25 vs BMI > 30 | P = 0.957 | |||
| Mortality · 2 year follow-upBMI 25-30 vs BMI > 30 | P = 0.681 |
— not stated in the abstract
- Implantable cardioverter-defibrillator (ICD) implantation — All patients
- 40.3%
WCD wearing time and adherence
- Similar across all BMI groups
WCD shock; Ventricular tachycardia (VT), VF and non-sustained VT (ns-VT)
- Similar/comparable across BMI groups
ICD implantation
- Slightly lower in BMI > 30, not significant
Mortality, multivariable analysis
- Long-term left ventricular ejection fraction (LVEF) significantly associated with reduced mortality
Original publication
Association of BMI with Adherence and Outcome in Heart Failure Patients Treated with Wearable Cardioverter Defibrillator. ESC Heart Fail. Published 30 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →