Coronary disease & ACSMeta-analysis
Association of body mass index on 10-year outcomes in patients treated with percutaneous coronary intervention and drug-eluting stents (the DECADE cooperation)
- Pooled analysis of randomised trials
- 10-year follow-up
Authors' conclusion
The baseline BMI of patients undergoing PCI with DES may have important implications for long-term secondary prevention strategies.
Study context
- Population
- Patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stent implantation
- Participants
- 9,486 patients · 5 RCTs
- Comparison
- Body mass index (BMI) categories vs normal weight
- Underweightn = 92
- Normal-weightn = 2,785reference
- Overweightn = 4,296
- Obesen = 2,313
- Outcome
- All-cause death
- Follow-up
- 10 years
Pooled result
As reported in the abstract
Each group vs normal-weightAdjusted hazard ratio (95% CI)
Underweight
1.58(1.01–2.47)
Overweight
0.84(0.78–0.90)
Further pooled results
CV death · 10 years
- Significantly lower risk in overweight vs normal-weight
Definite stent thrombosis within 30 days
- Significantly higher risk in overweight and obese vs normal-weight
TLR
- Significantly lower risk in obese vs normal-weight
BMI vs all-cause and CV death
- U-shaped, non-linear association
Original publication
Association of body mass index on 10-year outcomes in patients treated with percutaneous coronary intervention and drug-eluting stents (the DECADE cooperation). Eur J Prev Cardiol. Published 24 November 2025. doi:10.1093/eurjpc/zwaf753
Summarised from the published abstract; every number is checked against it