Heart failure & cardiomyopathiesCross-sectional study

Association of epicardial adipose tissue thickness and cardiac structure and function in early midlife: the cardiovascular risk in Young Finns Study

Eur J Prev CardiolPublished

  • Cross-sectional study

Authors' conclusion

Our results suggest associations between EAT thickness, increased LV wall thickness, LA size, and decreased mitral annular velocity in early adulthood.

Study context

Population
Young and middle-aged adults of the Cardiovascular Risk in Young Finns Studyechocardiography
Participants
1,667 participants
Exposure
Higher vs lower epicardial adipose tissue (EAT) thickness
Outcome
Associations between EAT thickness and echocardiographic metrics

Main finding

As reported in the abstract

Associations of higher EAT with echocardiographic metrics (adjusted for age, sex, waist circumference, SBP)
Left ventricular (LV) mean wall thickness, back-transformed β
0.72%, P = 0.002
LV relative wall thickness, back-transformed β
0.64%, P = 0.002
LV posterior wall thickness, β
0.0005, P = 0.0002
Left atrium (LA) size, β
0.02, P = 0.001
Mitral annular velocity (e'), back-transformed β (inverse association)
−1.0%, P = 0.02

Observational data: associations, not effects.

Original publication

Association of epicardial adipose tissue thickness and cardiac structure and function in early midlife: the cardiovascular risk in Young Finns Study. Eur J Prev Cardiol. Published 2 July 2025. doi:10.1093/eurjpc/zwaf394

Summarised from the published abstract; every number is checked against it