Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest

doi:10.1016/j.resuscitation.2026.111308

Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest

ResuscitationPublished 11 Sep 2026single-center retrospective study

Main finding · Unfavorable outcome (Pediatric Cerebral Performance Category Score ≥3 with change from pre-arrest) with increasing burden of hypotension below 10th percentile-for-age, using EHR-documented BPsResultOdds ratio 4.64 95% CI 1.21–17.6

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Authors' conclusion

Hypotension burden calculated using EHR-documented BPs was associated with unfavorable outcome after pediatric cardiac arrest and closely approximated hypotension burden from continuous high-resolution BPs.

Study context

Population: Children after cardiac arrest, followed for 24 h after return of spontaneous circulationpatients analyzed
Participants: 139 children

Exposure: EHR-documented blood pressures (BPs) vs continuous high-resolution BPs

Main finding

As reported in the abstract

Unfavorable outcome (Pediatric Cerebral Performance Category Score ≥3 with change from pre-arrest) with increasing burden of hypotension below 10th percentile-for-age, using EHR-documented BPs

Odds ratio

4.64

95% CI 1.21–17.6

P = 0.025

Increasing burden of hypotension below 10th percentile-for-age

odds ratio 4.64 (95% CI 1.21–17.6); P = 0.025

Observational data: associations, not effects.

Further findings

Outcome	EHR-documented BPs	Continuous high-resolution BPs
Hypotension burden, EHR-documented BPs vs. continuous high-resolution BPs	0.03 [0, 0.26] mmHg-h	0.04 [0, 0.38] mmHg-h

Hypotension burden, EHR-documented BPs vs. continuous high-resolution BPs — Hypotension burden was similar: p = 0.165

Bland-Altman analysis of hypotension burden, EHR-documented BPs vs. continuous high-resolution BPs

Mean difference: 0.22 ± 0.95
No significant bias toward either measurement modality: P = 0.096

Patient characteristics

Median age: 54 months
Male: 60.7%
Unfavorable outcome: 63%

Original publication

Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest. Resuscitation. Published 11 September 2026. doi:10.1016/j.resuscitation.2026.111308

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Summarised from the published abstract; every number is checked against it