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Acute cardiac care & resuscitationCohort study

Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest

ResuscitationPublished

  • single-center retrospective study
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Authors' conclusion

Hypotension burden calculated using EHR-documented BPs was associated with unfavorable outcome after pediatric cardiac arrest and closely approximated hypotension burden from continuous high-resolution BPs.

Study context

Population
Children after cardiac arrest, followed for 24 h after return of spontaneous circulationpatients analyzed
Participants
139 children
Exposure
EHR-documented blood pressures (BPs) vs continuous high-resolution BPs

Main finding

As reported in the abstract

Unfavorable outcome (Pediatric Cerebral Performance Category Score ≥3 with change from pre-arrest) with increasing burden of hypotension below 10th percentile-for-age, using EHR-documented BPs

Odds ratio

4.64

95% CI 1.21–17.6

P = 0.025

increasing burden of hypotension below 10th percentile-for-age
odds ratio 4.64 (95% CI 1.21–17.6); P = 0.025

Observational data: associations, not effects.

Further findings

OutcomeEHR-documented BPscontinuous high-resolution BPs
Hypotension burden, EHR-documented BPs vs. continuous high-resolution BPs0.03 [0, 0.26] mmHg-h0.04 [0, 0.38] mmHg-h
Hypotension burden, EHR-documented BPs vs. continuous high-resolution BPs — Hypotension burden was similar
p = 0.165

Bland-Altman analysis of hypotension burden, EHR-documented BPs vs. continuous high-resolution BPs

mean difference
0.22 ± 0.95
No significant bias toward either measurement modality
P = 0.096

Patient characteristics

median age
54 months
male
60.7%
unfavorable outcome
63%

Original publication

Association of hypotension burden calculated from intermittently documented blood pressures and outcome after pediatric cardiac arrest. Resuscitation. Published 11 September 2026. doi:10.1016/j.resuscitation.2026.111308
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Summarised from the published abstract; every number is checked against it